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Research KAIST Graduate School of Engineering Biology
Biofoundry
The Biofoundry is an automated Design–Build–Test–Learn (DBTL) platform that integrates research, education, and global collaboration in synthetic biology.
It serves as a core infrastructure for accelerating biotechnology innovation, performing three key functions: 1) Research Infrastructure, 2) Educational Platform, and 3) International Collaboration Hub.
Biofoundry-Based Education and Research
Overview
End-to-end automation through the KAIST Biofoundry, integrating research and hands-on training across the four core domains of synthetic biology — design, construction, analysis, and automation/process engineering.
Full-cycle DBTL experimentation and workflow execution
Integration of the KAIST BioFAB with the Korea National Biofoundry Infrastructure (KRIBB)
Practical, automation-based synthetic biology education using state-of-the-art instruments
DBTL Workflow (Hands-on Training)
DBTL cycle
Design
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Data-driven design
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AI-assisted design
Build
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High-throughput DNA synthesis
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Automated assembly of genetic constructs
Learn
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Functional analysis and ultra-fast screening
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Validation using cell-based and cell-free systems
Test
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Integrating data to extract design insights, optimize performance
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refine biological systems
Core Infrastructure & Tools
KAIST BioFAB Advanced automation systems and high-throughput analytics for research and training
KRIBB National Biofoundry (Beta Facility)
K-BioFAB
The KAIST Biofoundry (K-BioFAB) is a cutting-edge research and education facility located on the 2nd floor of the KAIST Meta-Convergence Building I.
It is equipped with open-access automation and analytical systems that enable the complete DBTL cycle — from design and construction to testing and learning.
K-BioFAB supports both innovative R&D in advanced biotechnology and hands-on training in practical synthetic biology, serving as a model for next-generation biofoundry education and collaboration.
K-BioFAB Workstations and Equipment Overview
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Colony Selection Workstation (Colony Picker, HIDEX, FLEX)
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Transformation Workstation (OT-2, BTX ECM 830)
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NGS Workstation (Zephyr G3, automatic PCR)
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DNA Workstation (Janus G3, LabChip)
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Multi Integration with Robotic Arm X-Arm 7 with linear motor
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Category (Description) |
Area [㎡] |
Remarks [pyeong] |
|---|---|---|
Research & Center Operations Room Workspace for domestic and international researchers participating in collaborative projects, and operation office for research centers |
105 |
31.8 |
K-BioFAB Automation Facility Equipped with state-of-the-art open-access automation instruments for research and education (e.g., fully automated multi-dispensing systems, nano liquid handlers, automated plate-handling robotic arms, and more) |
170.01 |
51.75 |
Biofoundry Process Facility Contains small-scale bioreactors and parallel microbial cultivation systems for process development and optimization |
58.45 |
17.7 |
Biofoundry Design–Build–Analyze Facility Shared research space equipped with high-end analytical and fabrication instruments for collaborative biofoundry research (e.g., HPLC, cell sorter, microplate reader, genome analyzer, etc.) |
184.38 |
55.69 |
Global Synthetic Biology Center Dedicated space for international collaboration and joint research with overseas partners |
86.4 |
26.2 |
Total Area |
604.24 |
183.14 |