About KAIST Graduate School of Engineering Biology

What is Engineering Biology?

Areas Critical for Solving Humanity’s Grand Challenges — Yet Facing Limitations

  • 01 Complexity of
    biological phenomena

    Low reproducibility

  • 02 Extreme
    diversity

    Reduced predictive efficiency

  • 03 Complex experimental
    procedures

    Difficulty in standardization

Long development timelines and high costs for technology advancement

The Need for Predictable and Safe High-Performance Cellular Systems, and Advanced Design–Manufacturing Technologies

  • High-throughput systemsHigh-throughput systems
  • Artificial Intelligence (AI)Artificial Intelligence (AI)
  • Component/Module-based engineeringComponent/Module-based engineering
Innovation in R&D cost, time, and speed

Innovation Driven by Synthetic Biology (Since 2010)

  • Top-Down Approach
    (Biological Engineering) Redesigning existing biological functions through genetic modification

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  • Bottom-Up Approach
    (Synthetic Biology) Building biological functions from scratch using DNA and essential biomolecular components

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Bio-Manufacturing Innovation (Since 2020)

  • Bio-manufacturing Innovation

    Production of diverse biochemicals and biomaterials replacing petroleum-based resources, including natural rubber precursors and high-performance optical films.

  • Pharmaceutical Innovation

    Rapid manufacturing of mRNA vaccines for pandemic response and securing reliable supply chains for raw materials and intermediates used in therapeutics.

  • Climate-Response Innovation

    Production of biofuels and biochemicals from greenhouse gases (e.g., CO₂) through synthetic biology–based conversion technologies.

01

Engineering Biology is an emerging discipline that integrates engineering principles into the life sciences to design, construct, and synthesize biological components and systems — encompassing the core concepts of synthetic biology. It represents a new frontier in science and technology, recently recognized as one of Korea’s National Strategic Technologies and as a key pillar of the Digital Bio initiative.

02

With advances in genome-based technologies and the accumulation of biological data, the paradigm of biotechnology R&D is shifting from discovery (genome decoding) to invention (genome synthesis). This transformation is redefining how we understand, engineer, and harness biological systems.

03

The convergence of biotechnology with digital, AI, and robotic automation technologies is enabling faster, large-scale, and cost-effective innovation — overcoming the traditional limitations of bio R&D. These developments are unlocking vast industrial applications across environmental, pharmaceutical, chemical, and energy sectors, paving the way for the creation of entirely new markets.

04

Through a next-generation educational system that fuses biology, AI, and engineering, the KAIST Graduate School of Engineering Biology aims to cultivate world-class “Engineering Biologists” — professionals equipped with quantitative, system-level, and integrative thinking and skills to lead the global transformation of the bioeconomy.